Which of the following does not lead to pigment gall stones
High-Yield Explanation
Predisposing factors for Black stones Hemolytic disorders(Heriditary spherocytosis, sickle cell anemia) Mechanical prosthetic hea valves Cirrhosis Gilbe's syndrome Cystic fibrosis Ileal disease or resection Brown stones Related to stasis and infection Gram negative bacteria (E.coli and Klebsiella) secretes beta-glucuronidase, which deconjugate soluble conjugated bilirubin Free unconjugated bilirubin precipitates and combines with calcium and bile to form brown pigment stones Stones form whenever static foreign bodies are present in the bile duct (stents or parasites such as clonorchis sinensis and Ascaris limbricoides) Ref: Sabiston 20th edition Pgno :1492