Anatomy Other topics and Adverse effects 697aca25 Most common side effect of 5-fluorouracil us A G.I toxicity B Bone marrow depression C Neurotoxicity D Cardiotoxicity High-Yield Explanation Ref-KDT 6/e p824 Diarrhea most common adverse effect of 5-FU It can also cause hand and foot syndrome and bone marrow suppression