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Medicine General 691b6162

Caplan Syndrome is Pneumoconiosis with

A
Lymphadenopathy
B
Congestive Cardiac Failure
C
Rheumatoid Ahritis
D
HIV
High-Yield Explanation
Answer is C (Rheumatoid Ahritis): Caplan's syndrome refers to the association of Pneumoconiosis and Rheumatoid Ahritis. Caplan's Syndrome is a rare subset of pulmonary nodulosis characterized by the development of nodules and pneumoconiosis following silica exposure in patients with Rheumatoid Ahritis. Caplan's Syndrome first described in coal miners but subsequently found in patients with silicosis includes seropositive Rheumatoid ahritis with charachteristic pneumoconiotic nodules. Silica has immunoadjuvant propeies and is often present in anthractic coal dust.

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