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Physiology Endocrinology metabolism 68e1e1db

Parathormone has all of the following effects, except -

A
Increased bone resorption
B
Increased Ca+2 reabsorption in kidney
C
Increased phosphate reabsorption in kidney
D
Increased calcitriol synthesis
High-Yield Explanation
Ans. is "c" i.e., Increased phosphate reabsorption in kidney o Paratharmone is 84 aminoacid polypeptide hormone secreted from parathyroid glands.o Its secretion is regulated by plasma Ca++ concentration -- fall in Ca++ concentration increases the secretion of paratharmone.o ActionsPTH increases resorption of calcium from bone --> most prominant action.PTH increases calcium reabsorption from distal tubules of kidney.PTH decreases phosphate reabsorption from proximal tubules of kidney.PTH has no direct effect on calcium absorption from intestine but increases it indirectly by enhancing the formation of calcitriol by activating la-hydroxylose.PTH decreases calcium level in milk, saliva, and ocular lens -- may be responsible for development of cataract in hypothyroidism.

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