A 29-year-old carpenter receives a traumatic laceration to her left arm. Which of the following is the most impoant factor that determines whether this wound will heal by primary or secondary intention?
High-Yield Explanation
Primary intention:- Healing by it occurs in wounds with closely apposed edges and minimal tissue loss. Such a wound requires only minimal cell proliferation and neovascularization to heal, and the result is a small scar. Secondary intention:- Healing by it occurs in a gouged wound, in which the edges are far apa and in which there is substantial tissue loss. This wound requires wound contraction, extensive cell proliferation, and neovascularization (granulation tissue) to heal. Granulation tissue is eventually resorbed and replaced by a large scar that is functionally and esthetically unsatisfactory. - The other choices are impoant determinants of the outcome of wound healing, but not a deciding factor in primary and secondary intention healing. Diagnosis: Healing by primary intention