A female with 45X0 genotype has primary amenorrhoea. Most likely diagnosis is:
High-Yield Explanation
The genotype XO belongs to the Turner's syndrome which is characteristic of gonadal dysgenesis, sho stature and external and internal dysmorphic features. The gonadal dysgenesis leads to primary amenorrhea. Ref: Clinical Obstetrics and Gynaecology by Brian A. Magowan, Philip Owen, James Drife, Pages 52-53 Disorders of Sex Development By John M. Hutson, Garry L. Warne, Sonia Grover, Page 91.