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Gynaecology & Obstetrics Medical Illness Complicating Pregnancy 681f5078

Which amongst the following statements are true regarding Acute Fatty liver of Pregnancy?

A
Occurs due to LCHAD deficiency (long-chain hydroxyl acyl coenzyme A dehydrogenase)
B
Macrovascular steatosis with peripoal sparing
C
Increase in fibrinogen, ammonia and SGOT
D
Most of the cases are asymptomatic
High-Yield Explanation
Acute Fatty liver of Pregnancy = Acute Metamorphosis = Acute yellow Atrophy Abnormal fatty acid oxidation LCHAD deficiency present in foetus.(long-chain hydroxyl acyl coenzyme A dehydrogenase) Microvascular steatosis with peripoal sparing Greasy soft yellow liver Complications--hypoglycaemia, hepatic encephalopathy, coagulopathy, renal failure, moality (10-75%), and increased risk of PIH. Treatment--fresh frozen plasma, cryoprecipitate, platelets, and blood.

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