A kinetic analysis of the effect of a drug on an enzyme's activity was performed, results as below. The drug would be best fit into which of the following group?

Ans. B. A noncompetitive inhibitora. Analysis of the data indicates that in the presence of the inhibitor, the Km of the enzyme is the same as in the absence of the inhibitor, but the Vmax is significantly reduced (the extrapolated lines intersect on the x-axis).b. These characteristics are the hallmark of noncompetitive inhibition.