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Pharmacology Adrenal 67d2101a

A patient Dharampal has been diagnosed to have bronchial asthma and is maintained on oral prednisolone 20 mg daily and inhaled salbutamol as required. The patient develops chest infection. Which of the following measures would you like to take?

A
Stop prednisolone
B
Reduce prednisolone dose to 5 mg/day
C
No change/increase in prednisolone dose
D
Substitute prednisolone with inhaled budesonide
High-Yield Explanation
* During conditions of stress or infection, dose of steroids should not be decreased. coicosteroids reduce the inflammatory response by inhibiting the activation of inflammatory cells and by reducing mediator production, microvascular leakage, and mucus formation.Coicosteriods helps in reducing infections. Rather, increase in dose may be required.

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