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Biochemistry General 675bc205

Mechanisms for regulating enzyme activity are ALL EXCEPT

A
Covalent modification
B
Allosteric activation
C
Competitive inhibition
D
Induction of genes for enzyme synthesis
High-Yield Explanation
Ans. is (c) Competitive inhibition [Ref: Harper 319`Ve p. 89-94; Lippincott 6"/e p. 62-64; Vasudevan 5thie p. 42-50; ShindeAs the name suggests, there is competition between inhibitor and normal substrate for the catalytic binding site of the enzyme. This is because both the inhibitor and the normal substrate have similar structural configuration. Therefore, enzyme cannot differentiate these two and both can bind to the enzyme. Both ES and EI complexes are formed. But only ES can form product.

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