Aschoff bodies in Rheumatic heart disease show all of the following features, except -

Aschoff body is the microscopic lesion that is diagnostic of rheumatic fever. It is characterized by an area of granular fibrinoid necrosis surrounded by :- a. Histiocytes b. Lymphocytes c. Plasma cells d. Fibroblasts e. Collagen f. Anitschkow cells - Anitschkow cells are actually histiocytes which have become multinucleated to form Aschoff giant cells. Aschoff bodies can occur in any layer* of the heart but they are most commonly seen in subendocardial region* and the myocardial interstitium.