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Biochemistry General 665b1339

Amino-acid substitute for tryptophan without altering proteins characteristics ?

A
Tyrosine
B
Phenylalanine
C
Methionine
D
Alanine
High-Yield Explanation
Ans. is `b' i.e., Phenylalanine Tryptophan is an aromatic amino acid, thus it can only be replaced with other aromatic amino acid.Other two aromatic amino acids are :?PhenylalanineTyrosineAmong these two, phenylalanine can substitute tryptophan but not tyrosine becausePhenylalanine and tryptophan both are hydrophobic (non-polar).Whereas, tyrosine is hydrophilic (Polar)."The only other aromatic residue that can substitude for tryptophan is phenylalanine. Tyrosine cannot substitute since it has hydrophilic propey"

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