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Pediatrics General 664a81cb

A five-year-old boy presents with precocious puberty and blood pressure of 130/80 mmHg Estimation of which of the following will help in diagnosis –

A
↑17 hydroxy-progesterone
B
↑ Cortisol
C
↑Aldosterone
D
↑ 11 deoxycortisol
High-Yield Explanation
At the age of 5-6 years, BP in excess of 115/75 mm Hg is considered as hypertension (This boy has BP 130/80). So, the boy in this question has : - Precocious puberty Hypertension Precocious puberty in male, with salt retention and hypertension, occurs due to deficiency of 11-β Hydroxylase which catalyzes the conversion of 11 deoxycortisol to cortisol.

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