Skin depigmentation, bilateral uveitis and tinnitus are features of –
High-Yield Explanation
Vogt Koyanagi - Harada (VKH) syndrome
It is an idiopathic multisystem disorder which includes cutaneous, neurological and ocular lesions.
The disease is comparatively more common in Japanese who are usually positive for HLA-DR4 and DW15.
Clinical features
Cutaneous lesions include: alopecia, poliosis and vitiligo.
Neurological lesions are in the form of meningism, encephalopathy, tinnitus, vertigo and deafness.
Ocular features are bilateral chronic granulomatous anterior uveitis, posterior uveitis and exudative retinal detachment.