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Pharmacology General 6607dab3

Which of the following represent the mechanism of action of tetracycline?

A
Inhibits peptidyl transferase
B
Causes misreading of mRNA
C
Causes termination of peptide chain elongation
D
Binds to A site and inhibits attachment of tRNA
High-Yield Explanation
Tetracyclines are bacteriostatic antibiotics. It inhibits protein synthesis by binding to 30S ribosomal subunit, and prevents the attachment of aminoacyl tRNA to the mRNA - ribosome complex. As a result peptide chain fails to grow. Ref: Essentials of Medical Pharmacology, 5th Edition, Page 668-73

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