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Pharmacology Anti-HIV Drugs 65e9c4e2

Which of the following drugs is most likely to cause additive anemia and neutropenia if administered to an AIDS patient taking zidovudine?

A
Acyclovir
B
Amantadine
C
Ganciclovir
D
Stavudine
High-Yield Explanation
* Ganciclovir is the drug of choice for CMV infections. * It should not be combined with zidovudine because both have bone marrow suppressant propey. * It is an analogue of acyclovir which is most active against CMV. but also inhibits other herpes viruses viz. H.simplex, H. zoster and EBV.

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