Drug contraindicated in G6PD deficiency?
High-Yield Explanation
Ans. is 'b > c > a' i.e., Primaquine > Quinine > Chloroquine o Among antimalarial drugs, primaquine, quinine and occasionally chloroquine can cause hemolytic anemia in G6PD deficiency. o But, primaquine has the highest potential to cause hemolytic anemia in patients with G6PD deficiency and, the patients with G6PD dificiency are highly senstive to primaquine. o The hemolytic potential in G6PD deficiency patients - Primaquine (maximum) > Quinine > Chloroquine (rare).