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Pathology Neoplasia 65b687e4

Which condition is associated with S-100 marker?

A
Multiple myeloma
B
Malignant melanoma
C
Prostate carcinoma
D
Medullary carcinoma thyroid
High-Yield Explanation
Ans is 'b' i.e. Malignant melanoma Markers for melanocytes1) S-100 - 90% of tumors are positive2) HMB-45 - More specific but less sensitive than S-1003) TA-904) Tyrosinase5) Microphthalmia transcription factor 6) Melan-A

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