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Biochemistry General 659b7e25

Which of the following actions are caused by 2-4-diinitrophenol?

A
Inhibition of ATP synthase
B
Inhibition of electron transpo
C
Uncoupling of oxidation and phosphorylation
D
Accumulation of ATP
High-Yield Explanation
2,4-dinitrophenol and valinomycin are two uncouplers which inhibit oxidative phosphorylation. 2,4-dinitrophenol is a potent uncoupler even in low concentrations by dissolving itself in the bi-lipid core of the inner cell membrane. Ref: Harper's Illustrated Biochemistry 27th/107; Biochemistry 3E By S C Rastogi, 2010, Page 224.

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