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Pharmacology Cytotoxic Anticancer Drugs 65904ecc

Bleomycin toxicity affects which organ predominantly?

A
Bone marrow
B
Lungs
C
Liver
D
RBC
High-Yield Explanation
Bleomycin is metabolized by bleomycin hydrolase. This enzyme is deficient in skin and lungs. Therefore, the major adverse effects of bleomycin are: Flagellated pigmentation of skin Pulmonary fibrosis

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