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Pathology Haematology 657b435f

Which one of the following red cell abnormalities is most indicative of hemolysis? -

A
Target cells
B
Acanthocytes
C
Schistocytes
D
Basophilic stippling
High-Yield Explanation
Target cells are morphologically abnormal RBC. In this hemoglobin is redistributed in such a way that only the periphery and central region of RBC appear hemoglobinized.Seen in thalassemia major , sickle cell anemia , post spleenenctomy, obstructive jaundice. Ref Robbins 9/e pg421

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