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Biochemistry General 657926d7

Glucose can be synthesized from all of the following except ?

A
Acetoacetate
B
Lactic Acid
C
Glycerol
D
Amino acid
High-Yield Explanation
Acetoacetate is a ketone body.During ketolysis,it is activated to acetoacetyl CoA which gives acetyl CoA.Acetyl CoA can not be reconveed back to pyruvate so acetoacetate can not be utilized for gluconeogenesis. Ref: Janson L.W., Tischler M.E. (2012). Chapter 2. Carbohydrates. In L.W. Janson, M.E. Tischler (Eds), The Big Picture: Medical Biochemistry.

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