Mallory Weiss Syndrome is caused due to tear in -
High-Yield Explanation
Mallory - Weiss syndrome
Is characterized by a mucosal tear at the gastroesophageal junction following a bout of forceful retching (or vomiting, coughing or straining).
The tear is partial thickness, extends through the mucosa and submucosa, but not through the muscular layer (compare this with Boerhaave syndrome in which the tear is full thickness penetrating completely through all the layers of the oesophagal wall with spillage of contents into the mediastinum).
The clinical picture consists of acute upper gastrointestinal bleeding following bouts of retching or vomiting.
The mean age of patients is older than 60 years. 80% are men" - Sabiston 17th/ep. 1254.
Majority of patients are alcoholics
Other frequent associations with Mallory - Weiss tears are → a Hiatal hernia, NSAIDs abuse, Disease related bleeding diathesis