True about Alphal antitrypsin deficiency is?
High-Yield Explanation
ANSWER: (D) All of the aboveREF: Robbins 7th ed p. 913Alpha 1 antitrypsin deficiency:Due to protease inhibitor deficiencyIncreased neutrophill elastaseNeonatal cholestasis may occur,Hepatocellular carcinoma may also developPulmonary disease may occur in form of emphysemaGene located on chromosome 14