Regarding premalignant oral lesions:

Oral submucous fibrosis is almost entirely confined to the Asian population and is characterized pathologically, by epithelial fibrosis with associated atrophy and hyperplasia of the overlying epithelium. LEUKOPLAKIA ERYTHROPLAKIA White keratotic plaque or patch that cannot be rubbed offQ and cannot be given another diagnostic name Risk factors: Smoking, alcohol, ill-fitting dentures, jagged toothQ Key pathologic features: Hyperkeratosis, parakeratosis, acanthosisQ In most cases, lesions regress spontaneously after stopping alcohol or tobacco consumption or correction of underlying causeQ. Baseline biopsy should be doneQ Lesions with moderate to severe dysplasia should be excisedQ. Oral Leukoplakia has low potential for malignancyQ. Red mucosal plaque, most commonly found on the soft palate and tonsillar pillarsQ. Does not arise from an obvious mechanical or inflammatory cause Cannot be ascribed to another clinical or pathological condition Key pathogenic features: severe cellular dysplasiaQ Because of increased malignant potential, all erythoplakic lesions must be biopsiedQ. Higher risk (17 times) of malignant transformation than leukoplakiaQ.