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Surgery General 64d7fb5e

Reticulocytosis is seen in all except :

A
P.N.H.
B
Hemolysis
C
Nutritional anemia
D
Dyserythropoietic syndrome
High-Yield Explanation
Nutritional anemia [Ref. Harrison 17h/e p 359, 360 &IOW p 333, 334, 607 and Ghai 6th/e p. 306J Congenital dyserythropoietic anemia Congential dyserythropoietic anemia represents a family of inherited refractory anemais characterized by ineffective erythropoiesis. Clinically it is characterized by varying degrees of anemia inspite of increased marrow elythroid activity. There is reticulocytosis but it is less than expected for the degree of anemia. Paroxysmal nocturnal hemoglobinuria Paroxymal nocturnal heoglobinuria is an acquired clonal stem cell disorder characerisized by the production of abnormal erythrocytes, granulocytes, and platelets. The red cell defect renders them more susceptible to complement mediated intravascular lysis. Clinically P.N.H. is characterized by chronic intravascular hemolysis. The blood usually shows a normocytic anemia with a reticulocytosis that is often less than expected for the degree of anemia.

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