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Skin General 64ce8770

Which of the following is true for acanthosis nigricans:

A
May be an indication of skin malignancy
B
Hypopigmentation
C
May be associated with Insulin resistant diabetes mellitus
D
Commonly occurs in lean and thin
High-Yield Explanation
Ans. C: May be associated with Insulin resistant diabetes mellitus Acanthosis nigricans is associated with obesity and insulin resistance in majority of the patients. In few cases, it may be a reflection of endocrinopathy such as acromegaly, cushing's syndrome polycystic ovarian syndrome. It occurs primarily in flexural areas as velvety hyperpigmentation. It may be a reflection of GIT malignancy.

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