Which of the following pathologic findings is/are the strongest contraindication to breast preservation (lumpectomy with breast radiation) as primary treatment for a newly diagnosed breast cancer?

Question

Accepted Answer

Grade 3, poorly differentiated, infiltrating ductal carcinoma

Answer

Extensive intraductal cancer around the invasive lesion

Answer

Tumor size less than 3 cm

Answer

Positive surgical margin for invasive cancer

Which of the following pathologic findings is/are the strongest contraindication to breast preservation (lumpectomy with breast radiation) as primary treatment for a newly diagnosed breast cancer?

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