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Pathology General 6432026a

Organelle where H202 is produced and destroyed is?

A
Peroxisome
B
Lysosome
C
Golgi body
D
Ribosome
High-Yield Explanation
Ans. is 'a' i.e., Peroxisome Peroxisome is a membrane bound organellel found in all eukaryotic cells. "Peroxisomes contain a group of enzymes that oxidize a variety of substrates and thereby form hydrogen peroxide. The H202 thus formed is efficiently decomposed within the organelle by catalase which is present in high concentration". Lysosomes can only form H,02 - They cannot degrade H202. Remember H202 is produced as well as destroyed in mitochondria and cytosol. It is produced from superoxide by enzyme SOD. It is destroyed by glutathione peroxidase.

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