In a child with active liver failure, the most important prognosis factor for death is –

Prognosis of hepatic failure in children Children with hepatic failure have somewhat better prognosis. The prognosis varies considerably with - i) Cause of liver failure ii) Stage of hepatic encephalopathy Poor prognostic factors for mortality If cause of liver failure is         —>       Wilson disease, idiopathic Stage IV coma —> Most common cause of death is brain stem herniation Age < I year Sepsis Severe hemorrhage Renal failure , Need for dialysis before transplantation For option b & c - "Pretransplant serum bilirubin concentration and the INR (prothrombin time) of coagulation are not predictive of post transplant survival".