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Gynaecology & Obstetrics Pharmacology in Gynaecology 63d991f8

A 20 years old nulliparous woman is an oral contraceptives pills. She is currently diagnosed as having pulmonary tuberculosis which antituberculous drug decreases the effect of OCP.

A
INH
B
Pyrazinamide
C
Ethambutol
D
Rifampicin
High-Yield Explanation
Ans. is 'd' i.e.,. Rifampicin (Ref KDT in, 11/01, p. 754).There is not much to explain in this one as you know refampicin is a microsomal enzyme inducer which enhances its own metabolism as well as that of many drugs like - Warfarin*OCP* in) Digitoxin*Sulfonylureas*Steroids*

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