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Pathology Respiration 63b6a2f7

A 56 year old chronic smoker, mass in bronchus resected. What is the possible marker:

A
Cytokeratin
B
Vimentin
C
Epithelial membrane Cadherin
D
Leukocyte
High-Yield Explanation
Ans. (a) Cytokeratin(Ref: Robbins 9th/pg 715-717)Chronic smoker with mass in bronchus suggests a diagnosis of small ell Ca and squamous cell ca.Diagnosis for squamous cell Ca is Keratinization ("squamous pearls") Q on light microscopy, diagnosed by cytokeratin and/or Intercellular bridges Q on electron microscopy is diagnostic.

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