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Medicine General 6398457f

Not seen in pre capillary pulmonary hypeension:

A
| pressure in pulm. circulation
B
| capillary pressure
C
Rt-vent.hyperophy
D
| Pulmonary wedge pressure
High-Yield Explanation
Answer is D (| Pulmonary wedge pressure) pulomary wedge pressure is not a feature of Precapillary Pulmonary hypeension. In precapillary pulmonary hypeension the abnormality that leads to elevated pulmonary pressure is located in the pulmonary aery or aerioles. The Left atrial pressure or Pulmonary capillary wedge pressure is essentially normal. Features Precapillary Passive (Post-capillary) Pathophysiology Abnormality that leads to elevated pulmonary Abnormalities that lead to elevated pulmonary aery pressure is located in the pulmoanry aery pressure are located beyond the aery or aerioles. pulmonary aeries. These are caused by diseases that lead to increased pulmonary venous pressure that in turn produces secondary elevation in pulmonary aerial pressure. Pulmonary aery mean pressure |/|| | Left Atrial Pressure (PCWP) Normal | PA left Atrial Pressure > 12mm <12mm Hg Gradient Conditions/Causes * Primary pulmonary hypeension * Left ventricular, failure * Disorders of ventilation * Mitral valve disease * Congenital hea disease with pulmonary * Cor triatriatum vascular disease * Obstruction of major pulmonary veins * Pulmonary embolism * Congenital pulmonary vein stenosis * Schistosmiasis * Left atrial myxoma or thrombosis * Collagen vascular disease * Pulmonary vasculitis * Sickle hemoglobinopathies * Poal hypeension * Ingestion of drugs and herbal remedies

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