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Gynaecology & Obstetrics Miscellaneous (Gynae) 638caed9

MgSO4 can cause all EXCEPT:

A
Cardiotoxicity
B
Renal failure
C
Respiratory depression
D
Abnormal DTR
High-Yield Explanation
Ans. a (cardiotoxicity). (Ref. KD Tripathi, 4th ed., 331, 659)MAGNESIUM SULFATE# Is not a hypotensive agent.# Works as a centrally acting anticonvulsant.# The therapeutic level of serum magnesium is 4--7 mEq/L.# Maternal Side Effects Related To MgSO4 -# Common- Flushing- Sense of warmth- Headache- Nystagmus- Nausea- Dizziness- Lethargy# Uncommon- Pulmonary edema- Neuromuscular blockage- Osteopenia# Toxicity of MgSO4- Respiratory rate <12- DTR's not detectable (usually noted when Magnesium level > 10 mEq/L)- Altered sensorium- Urine output < 25-30 cc/hour# Antidote: 10 ml of 10% solution of calcium gluconate IV over 3 minutes.

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