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Pathology Apoptosis 63882ed1

Apoptosis causes all except:

A
Activation of caspase
B
Local inflammatory response
C
Condensation of chromatin
D
Cleavage of chromatin by endonucleases
High-Yield Explanation
Features of Necrosis and Apoptosis Necrosis Apoptosis * Always pathological * May be physiological or pathological * Associated with disruption of cellular homeostasis (e.g. ischemia, hypoxia & poisoning) * Impoant for development, homeostasis & elimination of pathogens & tumor cells * Affects contiguous (adjacent) group of cells * Affect single cells * Cell size is increased * Cell size is shrunken * Passive * Active * Causes inflammatory reaction * No inflammatory reaction * Plasma membrane is disrupted * Plasma membrane is not disrupted * 'Smear pattern' on electrophoresis * Step ladder pattern on electrophoresis

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