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Pharmacology General 6360c16a

Which one of the following statements is false regarding vincristine -

A
It is an alkaloid
B
Its use is associated with neurotoxicity
C
It does not cause alopecia
D
It is a useful drug for induction of remission in acute lymphoblastic leukaemia
High-Yield Explanation
Ans. is 'c' i.e., It does not cause alopecia o Vincristine belongs to the plant alkaloid group of anticancer. o Useful for inducing remission in childhood ALL (not useful in maintenance therapy) o It can also be used for pediatric solid tumors (Wilm's tumor, neuroblastoma, rhabdomyosarcoma) and lymphomas. o Prominent adverse effects? o Peripheral neuropathy Alopecia SIADH

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