Intake of unsaturated fatty acid is associated with:

Diets deficient in fresh fruit, vegetables and polyunsaturated fatty acids are associated with an increased risk of cardiovascular disease. The introduction of a Mediterranean-style diet reduces cardiovascular events. However, dietary supplements, such as vitamins C and E, beta-carotene, folate and fish oils, do not reduce cardiovascular events and, in some cases, have been associated with harm. Reference: : Davidson P R I N C I P L E S   and Practice O F M E D I C I N E 23rd edition page no  486