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General Medicine General 62ee948c

True about the Sickle cell disease are all, Except -

A

Single nucleotide change results in change of Glutamate to Valine

B

Sticky patch is generated as a result of replacement of a non polar residue with a polar residue

C

HbS confers resistance against malaria in heterozygotes

D

RFLP results from a single base change

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