Pharmacology General pharmacology 62c11404

A competitive antagonist is a substance that

Interacts with receptors and produces submaximal effect

Binds to the same receptor site and progressively inhibits the agonist response

Binds to the nonspecific sites of tissue

Binds to one receptor subtype as an agonist and to another as an antagonist

High-Yield Explanation

In the presence of a fixed concentration of agonist, increasing concentrations of a competitive antagonist progressively inhibit the agonist responseBasic and clinical pharmacology Katzung 13th edition pg 23

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