A 26 year old male with AML was started on Doxorubicin based chemotherapy. After few months he came with breathlessness and swelling of feet. Which of the following side effect of doxorubicin has resulted in these symptoms
High-Yield Explanation
The above symptoms are because of Hypertrophic cardiomyopathy, caused by Doxorubicin because of free radical production. Dexrazoxane is a free radical scavenger given to prevent the cardiotoxicity.