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Microbiology All India exam 629d13ac

The antiretroviral drug that can bind to both CCR2 and CCR5 is

A
Cenicriviroc
B
Vicriviroc
C
Ibalizumab
D
Bevirimat
High-Yield Explanation
Cenicriviroc Cenicriviroc binds to both CCR2 and CCR5. It is a fusion/entry inhibitor. CCR2 binding may contribute to the anti-inflammatory effect.VicrivirocVicriviroc binds to CCR5. It is a fusion/entry inhibitor. Not found to be efficacious in clinical trials, hence fuher trials were discontinued.Ibalizumab Ibalizumab is a monoclonal antibody against CD4. It is a fusion/entry inhibitor.BevirimatBevirimat is a maturation inhibitor. It binds to gag protein.

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