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Pathology Amyloidosis 629a82f1

The best investigation for the diagnosis of amyloidosis is:

A
Colonoscopy
B
Rectal biopsy
C
Upper GI endoscopy
D
CT scan
High-Yield Explanation
The histological examination of the biopsy material is the commonest and confirmatory method for the diagnosis in a suspected case of amyloidosis. The sites for the biopsy can be:- Renal tissue Rectum Abdominal fat aspiration Gingiva. The rectum Q is the best site for taking the biopsy in the options provided. However as per Harrison latest edition, the abdominal fat aspirate is currently the best option for systemic amyloidosis.

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