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Pharmacology Central Nervous system 627930de

A patient of schizophrenia was staed on haloperidol 5 mg. Next day, he presented with uprolling of eyes. Complete neurological examination revealed no spasticity or any other abnormality. Visual acuity and opthalmoscopic findings are normal. Most likely diagnosis is

A
Akathisia
B
Acute dystonia
C
Seizure
D
Tardive dyskinesia
High-Yield Explanation
Acute muscular dystonias Bizarre muscle spasms, mostly involving lingua-facial muscles -grimacing, tongue thrusting, toicollis, locked jaw; occurs within a few hours of a single dose or at the most in the first week of therapy. It is more common in children below 10 years and in girls, paicularly after parenteral administration; overall incidence is 2%. It lasts for one to few hours and then resolves spontaneously. One of the central anticholinergics, promethazine or hydroxyzine injected i.m. clears the reaction within 10-15 min. REF KD TRIPATHHI 8TH ED.

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