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Pathology General 6251b91a

Following is true about bronchial carcinoids -

A
Highly radiosensitive
B
Metastasis common
C
Carcinoid syndrome does not manifest
D
Commonly arise from terminal bronchioles
High-Yield Explanation
Ans. is 'c' i.e., Carcinoid syndrome does not manifest Bronchial carcinoid o Most patients < 40 years o Not related to smoking o Most tumors are confined to main stem bronchi and commonly project into lumen. Some tumors penetrate the bronchial wall to fan out in the peri-bronchial tissue producing the collar-button lesion. o Most bronchial carcinoids :Do not have secretory activity. Do not metastasize to distant sites (follow a benign course for long periods). Are amenable to resection. o Most common presentation is intraluminal growth which can cause cough, hemoptysis, secondary infections, bronchiectasis, emphysema and atelectasis. o Though very rare, some bronchial carcinoids may also present : i) Carcinoid syndrome ( due to release of vasoactive amines) :- Flushing, diarrhea, cyanosis ii) Symptoms due to metastasis.

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