What should be measured in a newborn who presents with hyperbilirubinemia –

Bilirubin is a tetrapyrrole and a breakdown product of heme catabolism. Most bilirubin (70%-90%) is derived from hemoglobin degradation and, to a lesser extent, from other hemoproteins. In the serum, bilirubin is usually measured as both direct bilirubin (DBil) and total-value bilirubin Direct bilirubin correlates with conjugated bilirubin but tends to overestimate actual conjugated bilirubin, as it includes both the conjugated bilirubin and bilirubin covalently bound to albumin (delta-bilirubin). Indirect bilirubin correlates with unconjugated bilirubin but tends to underestimate unconjugated bilirubin, as a