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Physiology Hormones 61faef90

Following is true of hormone leptin except:

A
It is found in increased levels in obese
B
Site of action is hypothalamus
C
It is produced by adipose all
D
It increases appetite
High-Yield Explanation
Ans: D (It increases appetite) Ref: Pal GK, Functions of Hypothalamus, In: Textbook of Medical Physiology, Ahuja Publishing House, 118:889Explanation:LeptinProtein of 167 amino acidsManufactured primarily in the adipocytesHigh leptin level occurs in obesity - | sympathetic activity; | food intakeLow- leptin level occurs in starvation | parasympathetic activity; | food intakeActs on hypothalamus, arcuate nucleus identifies plasma leptin concentration.Regulates onset of pubertyStimulates thyroid functionControls glucocorticoid secretion

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