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Pharmacology General Pharmacology 61d213ea

Which of the following drugs is an inhibitor of cytochrome p450 enzymes?

A
Ketoconazole
B
Rifampicin
C
Phenytoin
D
Phenobarbitone
High-Yield Explanation
Ans. (A) Ketoconazole(Ref: KDT 8th/e p30)Ketoconazole is a powerful microsomal enzyme inhibitor whereas rifampicin, phenobarbitone and phenytoin are enzyme inducers.

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