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Medicine General 61ceb3ab

All are causes of Gynaecomastia, except

A
Cimetidine therapy
B
Androgen therapy
C
Leprosy
D
Small cell carcinoma lung
High-Yield Explanation
Even androgen therapy can cause gynecomastia but among all options given in the question, the best answer is androgen therapy. Some important causes of Gynaecomastia Leprosy   Testicular tumours    Lung cancer - Small cell type Adrenal disease   Liver disease Hyperthyroidism  Hyperprolactinemia   Castration      Orchitis          Drugs - Digitalis   Spironolactone    Cimetidine       Clomiphene       Methyldopa  Androgens   Gonadotrophins   Estrogens  Progesterones    Ketoconazole.                                                                                                                                            Gynecomastia refers to the enlargement of the male breast Hormone effects Like the female breast, the male breast is also subject to hormonal influences, and gynecomastia occurs as a result of an imbalance between estrogens which stimulate breast tissue and androgens which counteract these effects. Usually, gynecomastia is caused by an estrogen excess and is usually the result of an increased estrogen/androgen ratio, caused by - Increased estrogen Decreased androgen hCG producing tumours (hCG stimulates Leydig cells to produce estrogen).

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