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Pharmacology General 614f318c

One has to be careful about hypoglycaemia when patient gives history of taking this drug:

A
Chlorpropamide (Daonil)
B
Furosemide (Lasix)
C
Corticosteroids (Wysolone)
D
Theophylline (Deriphylline)
High-Yield Explanation
Chlorpropamide: It is a long-acting sulfonylurea oral hypoglycaemic, found to reduce urine volume in DI of pituitary origin, but not in renal DI. It sensitizes the kidney to ADH action.  DI = Diabetes Insipidus. Due to its long duration of action, one has to be careful about hypoglycaemia, when patient gives history of taking this drug. Reference: Essentials of Medical Pharmacology Eighth Edition KD  TRIPATHI  page no 644

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