Which of the following statement is true regarding “Catecholamines” ?

Synthesis of catecholamine is organ specific, so option A is correct. Production of catecholamine begins once tyrosine hydroxylase acts on tyrosine and forms DOPA so option B is wrong. All catecholamine are metabolized to vanillyl mandelic acid (VMA) which gets excreted in urine unchanged. VMA has neither glucogenic nor ketogenic fate. So option C is also wrong. Out of various catecholamine, only epinephrine has got one methyl group. Dopamine and norepinephrine does not contain any methyl group. So option D is also wrong.